Watch Intently (2)pentobarbital will lower the extent or result of suvorexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Strong CYP3A4 inducers may well lessen suvorexant efficacy; if elevated suvorexant dose essential, never exceed 20 mg/working daypentobarbital will decrease the extent or impact of bupr